Like his earlier books on Steve Jobs, Leonardo da Vinci, and Albert Einstein, Isaacson leans heavily on profiles to tell the broader story. It is being tested in food and animals and, in a limited way, to correct or treat genetic defects such as sickle-cell anemia. Isaacson makes it clear that RNA has played a starring role both in The Code Breaker, as well as in the life and career of its central character, Jennifer Doudna, who was the co-recipient - with Emmanuelle Charpentier - of the 2020 Nobel Prize for Chemistry for the discovery of CRISPR, the gene-editing technology.ĬRISPR is the unwieldy acronym for Clustered Regularly Interspaced Short Palindromic Repeats, which is essentially a natural way of altering or replacing DNA sequences in a cell.
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